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1-(3-(Trimethylsilyl)propionyl)-lysergic acid diethylamide

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1S-LSD
1-(3-(Trimethylsilyl)propionyl)-lysergic acid diethylamide
Molecular structure via molpic based on CDK
Physical properties
[]
451.7 g/mol [1]
Structural Identifiers
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C26H37N3O2Si [1]
(6aR,9R)-N,N-diethyl-7-methyl-4-(3-trimethylsilylpropanoyl)-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-9-carboxamide [1]
CCN(CC)C(=O)[C@H]1CN([C@@H]2CC3=CN(C4=CC=CC(=C34)C2=C1)C(=O)CC[Si](C)(C)C)C [1]
InChI=1S/C26H37N3O2Si/c1-7-28(8-2)26(31)19-14-21-20-10-9-11-22-25(20)18(15-23(21)27(3)16-19)17-29(22)24(30)12-13-32(4,5)6/h9-11,14,17,19,23H,7-8,12-13,15-16H2,1-6H3/t19-,23-/m1/s1 [1]
InChIKeyRYNRSMKGPSUXLC-AUSIDOKSSA-N [1]

1-(3-(Trimethylsilyl)propionyl)-lysergic acid diethylamide (also known as 1-[3-(Trimethylsilyl)propanoyl] lysergic acid diethylamide, 1S-LSD, Schembl31390429 or Dtxsid601376571) is a psychedelic substance of the lysergamide class.

Chemistry

 []

1-(3-(Trimethylsilyl)propionyl)-lysergic acid diethylamide is a achiral mixture.

Subjective effects []

Pilz / 1-(3-(Trimethylsilyl)propionyl)-lysergic acid diethylamide []
  • Routes:
    • Sublingual (0.01-0.02mg)

Legal status []

  • Germany: 1-(3-(Trimethylsilyl)propionyl)-lysergic acid diethylamide is a Neuer-Psychoaktiver-Stoff under the "Neue-psychoaktive-Stoffe-Gesetz (NpSG)".

See also []

  • Substituted lysergamides
  • Anodyne

    • External links []

    References []

    1. National Center for Biotechnology Information. PubChem Compound Summary for CID 172875719, 1-[3-(Trimethylsilyl)propanoyl] lysergic acid diethylamide. Accessed March 22, 2026. https://pubchem.ncbi.nlm.nih.gov/compound/172875719